Analytical Method Development for Sodium Valproate through Chemical Derivatization

Background. Sodium valproate has anticonvulsant activity and is structurally different to conventional antiepileptic drugs. The problem with valproic acid is the lack of a chromophore, which means that gas chromatography is the sole assay methodology. The introduction of benzoyl and phenyl groups to...

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Bibliographic Details
Main Authors: Murad Abualhasan, Nihaya Wasif Odeh, Ghadeer Naser Younis, Oyoun Fadel Zeidan
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:International Journal of Analytical Chemistry
Online Access:http://dx.doi.org/10.1155/2020/5672183