Systematically differentiating functions for alternatively spliced isoforms through integrating RNA-seq data.

Integrating large-scale functional genomic data has significantly accelerated our understanding of gene functions. However, no algorithm has been developed to differentiate functions for isoforms of the same gene using high-throughput genomic data. This is because standard supervised learning requir...

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Bibliographic Details
Main Authors: Ridvan Eksi, Hong-Dong Li, Rajasree Menon, Yuchen Wen, Gilbert S Omenn, Matthias Kretzler, Yuanfang Guan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24244129/?tool=EBI