Ablation of tau causes an olfactory deficit in a murine model of Parkinson’s disease

Ablation of tau causes an olfactory deficit in a murine model of Parkinson’s disease

Abstract Parkinson’s disease is diagnosed upon the presentation of motor symptoms, resulting from substantial degeneration of dopaminergic neurons in the midbrain. Prior to diagnosis, there is a lengthy prodromal stage in which non-motor symptoms, including olfactory deficits (hyposmia), develop. Th...

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Bibliographic Details
Main Authors: Leah C. Beauchamp, Jacky Chan, Lin W. Hung, Benjamin S. Padman, Laura J. Vella, Xiang M. Liu, Bradley Coleman, Ashley I. Bush, Michael Lazarou, Andrew F. Hill, Laura Jacobson, Kevin J. Barnham
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Acta Neuropathologica Communications
Subjects:
Tau
Parkinson’s disease
Olfaction
Autophagy
Neurodegeneration
Online Access:http://link.springer.com/article/10.1186/s40478-018-0560-y

Internet

http://link.springer.com/article/10.1186/s40478-018-0560-y

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