Developing a highly stable PLGA-mPEG nanoparticle loaded with cisplatin for chemotherapy of ovarian cancer.

Cisplatin is a potent anticancer drug, but its clinical application has been limited due to its undesirable physicochemical characteristics and severe side effects. Better drug formulations for cisplatin are highly desired.Herein, we have developed a nanoparticle formulation for cisplatin with high...

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Bibliographic Details
Main Authors: Lihua Cheng, Chengmeng Jin, Wen Lv, Qiuping Ding, Xu Han
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3180455?pdf=render