Partial loss in septo-hippocampal cholinergic neurons alters memory-dependent measures of brain connectivity without overt memory deficits
The functional relevance of septo-hippocampal cholinergic (SHC) degeneration to the degradation of hippocampus-dependent declarative memory (DM) in aging and Alzheimer's disease (AD) remains ill-defined. Specifically, selective SHC lesions often fail to induce overt memory impairments in animal...
Main Authors: | Laurent Brayda-Bruno, Nicole Mons, Benjamin K. Yee, Jacques Micheau, Djoher Nora Abrous, Xavier Nogues, Aline Marighetto |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2013-06-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S096999611300034X |
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