Human pregnane X receptor is expressed in breast carcinomas, potential heterodimers formation between hPXR and RXR-alpha

<p>Abstract</p> <p>Background</p> <p>The human pregnane X receptor (hPXR) is an orphan nuclear receptor that induces transcription of response elements present in steroid-inducible cytochrome P-450 gene promoters. This activation requires the participation of retinoid X...

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Bibliographic Details
Main Authors: Fraile Benito, Alba Emilio, González Francisco J, Pérez Julio, Zamora Javier, Lobo María VT, Conde Isabel, Paniagua Ricardo, Arenas María I
Format: Article
Language:English
Published: BMC 2008-06-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/8/174