Prediction of drug-target interactions and drug repositioning via network-based inference.

Prediction of drug-target interactions and drug repositioning via network-based inference.

Drug-target interaction (DTI) is the basis of drug discovery and design. It is time consuming and costly to determine DTI experimentally. Hence, it is necessary to develop computational methods for the prediction of potential DTI. Based on complex network theory, three supervised inference methods w...

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Bibliographic Details
Main Authors: Feixiong Cheng, Chuang Liu, Jing Jiang, Weiqiang Lu, Weihua Li, Guixia Liu, Weixing Zhou, Jin Huang, Yun Tang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22589709/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22589709/?tool=EBI

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