A Time to Kill: Targeting Apoptosis in Cancer

The process of apoptosis is essential for maintaining the physiologic balance between cell death and cell growth. This complex process is executed by two major pathways that participate in activating an executioner mechanism leading to chromatin disintegration and nuclear fragmentation. Dysregulatio...

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Bibliographic Details
Main Authors: Jean L. Koff, Sampath Ramachandiran, Leon Bernal-Mizrachi
Format: Article
Language:English
Published: MDPI AG 2015-01-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/16/2/2942