Tissue inhibitor of metalloproteinase 1 is preferentially expressed in Th1 and Th17 T-helper cell subsets and is a direct STAT target gene.

Tissue inhibitor of metalloproteinase 1 is preferentially expressed in Th1 and Th17 T-helper cell subsets and is a direct STAT target gene.

CD4(+) T helper (Th) cells differentiate into distinct effector subsets that are critical for host defense, but are also implicated in the pathogenesis of autoimmune disorders. Thelper17 (Th17) cells in particular are emerging as important drivers of multiple diseases including psoriasis, spondyloar...

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Bibliographic Details
Main Authors: Adewole Adamson, Kamran Ghoreschi, Matthew Rittler, Qian Chen, Hong-Wei Sun, Golnaz Vahedi, Yuka Kanno, William G Stetler-Stevenson, John J O'Shea, Arian Laurence
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3608653?pdf=render

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http://europepmc.org/articles/PMC3608653?pdf=render

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