Whole blood microRNA expression pattern differentiates patients with rheumatoid arthritis, their seropositive first-degree relatives, and healthy unrelated control subjects

Whole blood microRNA expression pattern differentiates patients with rheumatoid arthritis, their seropositive first-degree relatives, and healthy unrelated control subjects

Abstract Background Epigenetic mechanisms can integrate gene-environment interactions that mediate disease transition from preclinical to clinically overt rheumatoid arthritis (RA). To better understand their role, we evaluated microRNA (miRNA, miR) expression profile in indigenous North American pa...

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Bibliographic Details
Main Authors: Vidyanand Anaparti, Irene Smolik, Xiaobo Meng, Victor Spicer, Neeloffer Mookherjee, Hani El-Gabalawy
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Arthritis Research & Therapy
Subjects:
MicroRNA
Rheumatoid arthritis
Epigenetics
miRNA
miR-103a-3p
Whole blood
Online Access:http://link.springer.com/article/10.1186/s13075-017-1459-x

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http://link.springer.com/article/10.1186/s13075-017-1459-x

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