Effects of lovastatin therapy on guinea pig low density lipoprotein composition and metabolism.

Lovastatin therapy is known to induce hepatic low density lipoprotein (LDL) receptor mRNA and LDL receptor activity. Yet, in studies in humans and animals it has been difficult to demonstrate an enhancement of the plasma fractional catabolic rate (FCR) of an injected LDL tracer during lovastatin the...

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Bibliographic Details
Main Authors: L Berglund, M F Sharkey, R L Elam, J L Witztum
Format: Article
Language:English
Published: Elsevier 1989-10-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520382420