Myeloid - derived suppressor cells in Type 1 diabetes are an expanded population exhibiting diverse T-cell suppressor mechanisms.

Myeloid - derived suppressor cells in Type 1 diabetes are an expanded population exhibiting diverse T-cell suppressor mechanisms.

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Myeloid-derived suppressor cells (MDSC) represent a heterogeneous group of immature myeloid cells with immunoregulatory function in cancer and autoimmune diseases. In humans, two subsets of MDSC were determined based on the characteristic surface markers, monocytic MDSC (M-MDSC) and granulocytic MDS...

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Main Authors: Anna Grohová, Klára Dáňová, Irena Adkins, Zdeněk Šumník, Lenka Petruželková, Barbora Obermannová, Stanislava Koloušková, Radek Špíšek, Lenka Palová-Jelínková
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0242092

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https://doi.org/10.1371/journal.pone.0242092

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