Low Postseroconversion CD4+ T-cell Level Is Associated with Faster Disease Progression and Higher Viral Evolutionary Rate in HIV-2 Infection

Low Postseroconversion CD4+ T-cell Level Is Associated with Faster Disease Progression and Higher Viral Evolutionary Rate in HIV-2 Infection

The relationship between HIV evolution and disease progression is fundamental to our understanding of HIV immune control and vaccine design. There are no clear definitions for faster and slower HIV-2 disease progression and for the relationship of the rate of progression with HIV-2 evolution. To add...

Full description

Bibliographic Details
Main Authors: Angelica A. Palm, Philippe Lemey, Marianne Jansson, Fredrik Månsson, Anders Kvist, Zsófia Szojka, Antonio Biague, Zacarias José da Silva, Sarah L. Rowland-Jones, Hans Norrgren, Joakim Esbjörnsson, Patrik Medstrand
Format: Article
Language:English
Published: American Society for Microbiology 2019-01-01
Series:mBio
Subjects:
disease progression
human immunodeficiency virus
viral evolution
Online Access:https://doi.org/10.1128/mBio.01245-18

Internet

https://doi.org/10.1128/mBio.01245-18

Similar Items