Host protein ABCE1 interacts with the viral phosphoprotein and promotes rabies virus replication

Host protein ABCE1 interacts with the viral phosphoprotein and promotes rabies virus replication

Rabies virus (RABV) phosphoprotein (P) plays an important role in disrupting host interferon (IFN)-mediated antiviral immune response. ABCE1 is known as an RNase L inhibitor that negatively regulates the 2′,5′-oligoadenylate (2-5A)/RNase L antiviral system related to the IFN signaling pathway. In th...

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Bibliographic Details
Main Authors: Xing Liu, Jiwen Zhang, Fang Li, Yibrah Tekle Hagoss, Weldu Tesfagaber, Lulu Wang, Zilong Wang, Dongming Zhao, Zhigao Bu
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Biosafety and Health
Subjects:
Rabies virus
ABCE1
Replication
Phosphoprotein
Interaction
Online Access:http://www.sciencedirect.com/science/article/pii/S2590053620300847

Internet

http://www.sciencedirect.com/science/article/pii/S2590053620300847

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