Host protein ABCE1 interacts with the viral phosphoprotein and promotes rabies virus replication
Rabies virus (RABV) phosphoprotein (P) plays an important role in disrupting host interferon (IFN)-mediated antiviral immune response. ABCE1 is known as an RNase L inhibitor that negatively regulates the 2′,5′-oligoadenylate (2-5A)/RNase L antiviral system related to the IFN signaling pathway. In th...
Main Authors: | Xing Liu, Jiwen Zhang, Fang Li, Yibrah Tekle Hagoss, Weldu Tesfagaber, Lulu Wang, Zilong Wang, Dongming Zhao, Zhigao Bu |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-09-01
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Series: | Biosafety and Health |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2590053620300847 |
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