Gas6 Inhibits Toll-Like Receptor-Mediated Inflammatory Pathways in Mouse Microglia via Axl and Mer

Gas6 Inhibits Toll-Like Receptor-Mediated Inflammatory Pathways in Mouse Microglia via Axl and Mer

Background: Microglia are well known key regulators of neuroinflammation which feature in multiple neurodegenerative disorders. These cells survey the CNS and, under inflammatory conditions, become “activated” through stimulation of toll-like receptors (TLRs), resulting in changes in morphology and...

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Bibliographic Details
Main Authors: Shannon E. Gilchrist, Salman Goudarzi, Sassan Hafizi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Cellular Neuroscience
Subjects:
microglia
Gas6
TAM receptors
toll-like receptors
LPS
inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.576650/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2020.576650/full

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