Novel features of a PIWI-like protein homolog in the parasitic protozoan Leishmania.

In contrast to nearly all eukaryotes, the Old World Leishmania species L. infantum and L. major lack the bona fide RNAi machinery genes. Interestingly, both Leishmania genomes code for an atypical Argonaute-like protein that possesses a PIWI domain but lacks the PAZ domain found in Argonautes from R...

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Bibliographic Details
Main Authors: Prasad K Padmanabhan, Carole Dumas, Mukesh Samant, Annie Rochette, Martin J Simard, Barbara Papadopoulou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3528672?pdf=render