Deciphering the Mammary Stem Cell Niche: A Role for Laminin-Binding Integrins

Summary: Integrins, which bind laminin, a major component of the mammary basement membrane, are strongly expressed in basal stem cell-enriched populations, but their role in controlling mammary stem cell function remains unclear. We found that stem cell activity, as evaluated in transplantation and...

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Bibliographic Details
Main Authors: Mathilde Romagnoli, Stéphanie Cagnet, Aurélie Chiche, Laura Bresson, Sylvain Baulande, Pierre de la Grange, Adèle De Arcangelis, Maaike Kreft, Elisabeth George-Labouesse, Arnoud Sonnenberg, Marie-Ange Deugnier, Karine Raymond, Marina A. Glukhova, Marisa M. Faraldo
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671119300566