Methylation profiles reveal distinct subgroup of hepatocellular carcinoma patients with poor prognosis.

Hepatocellular Carcinoma (HCC) is one of the leading causes of cancer-associated mortality worldwide. However, the role of epigenetic changes such as aberrant DNA methylation in hepatocarcinogenesis remains largely unclear. In this study, we examined the methylation profiles of 59 HCC patients. Usin...

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Bibliographic Details
Main Authors: Way-Champ Mah, Thomas Thurnherr, Pierce K H Chow, Alexander Y F Chung, London L P J Ooi, Han Chong Toh, Bin Tean Teh, Yogen Saunthararajah, Caroline G L Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4122406?pdf=render