Analysis of ancestral and functionally relevant CD5 variants in systemic lupus erythematosus patients.

Analysis of ancestral and functionally relevant CD5 variants in systemic lupus erythematosus patients.

<h4>Objective</h4>CD5 plays a crucial role in autoimmunity and is a well-established genetic risk factor of developing RA. Recently, evidence of positive selection has been provided for the CD5 Pro224-Val471 haplotype in East Asian populations. The aim of the present work was to further...

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Main Authors: Maria Carmen Cenit, Mario Martínez-Florensa, Marta Consuegra, Lizette Bonet, Elena Carnero-Montoro, Noelia Armiger, Miguel Caballero-Baños, Maria Teresa Arias, Daniel Benitez, Norberto Ortego-Centeno, Enrique de Ramón, José Mario Sabio, Francisco J García-Hernández, Carles Tolosa, Ana Suárez, Miguel A González-Gay, Elena Bosch, Javier Martín, Francisco Lozano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0113090

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https://doi.org/10.1371/journal.pone.0113090

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