Regulation of Memory Formation by the Transcription Factor XBP1

Regulation of Memory Formation by the Transcription Factor XBP1

Contextual memory formation relies on the induction of new genes in the hippocampus. A polymorphism in the promoter of the transcription factor XBP1 was identified as a risk factor for Alzheimer’s disease and bipolar disorders. XBP1 is a major regulator of the unfolded protein response (UPR), mediat...

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Bibliographic Details
Main Authors: Gabriela Martínez, René L. Vidal, Pablo Mardones, Felipe G. Serrano, Alvaro O. Ardiles, Craig Wirth, Pamela Valdés, Peter Thielen, Bernard L. Schneider, Bredford Kerr, Jose L. Valdés, Adrian G. Palacios, Nibaldo C. Inestrosa, Laurie H. Glimcher, Claudio Hetz
Format: Article
Language:English
Published: Elsevier 2016-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716000498

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http://www.sciencedirect.com/science/article/pii/S2211124716000498

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