Sequence-specific inhibition of small RNA function.
Hundreds of microRNAs (miRNAs) and endogenous small interfering RNAs (siRNAs) have been identified from both plants and animals, yet little is known about their biochemical modes of action or biological functions. Here we report that 2'-O-methyl oligonucleotides can act as irreversible, stoichi...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2004-04-01
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| Series: | PLoS Biology |
| Online Access: | http://europepmc.org/articles/PMC350664?pdf=render |