Neurochemical Analysis of Primary Motor Cortex in Chronic Low Back Pain

Neurochemical Analysis of Primary Motor Cortex in Chronic Low Back Pain

The involvement of the primary motor cortex (M1) in chronic low back pain (LBP) is a relatively new concept. Decreased M1 excitability and an analgesic effect after M1 stimulation have been recently reported. However, the neurochemical changes underlying these functional M1 changes are unknown. The...

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Bibliographic Details
Main Authors: Anda E. Popescu, Linda VanDillen, Patrick Gorman, Carmen M. Cirstea, Byron J. Gajewski, Steven Z. George, Kenneth E. McCarson, Neena K. Sharma, William M. Brooks
Format: Article
Language:English
Published: MDPI AG 2012-08-01
Series:Brain Sciences
Subjects:
chronic low back pain
primary motor cortex
magnetic resonance spectroscopy
N-acetylaspartate
myo-inositol
Online Access:http://www.mdpi.com/2076-3425/2/3/319

Internet

http://www.mdpi.com/2076-3425/2/3/319

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