Leucine minimizes denervation-induced skeletal muscle atrophy of rats through akt/mtor signaling pathways

Leucine minimizes denervation-induced skeletal muscle atrophy of rats through akt/mtor signaling pathways

The aim of the present study was to evaluate the effect of leucine treatment (0.30 mM) on muscle weight and signaling of myoproteins related to synthesis and degradation pathways of soleus muscle following seven days of complete sciatic nerve lesion.Wistar rats (n=24) of 3 to 4 months of age (192 ±...

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Bibliographic Details
Main Authors: Carolina Barbosa Ribeiro, Daiane Cristina Christofoletti, Vitor Alexandre Pezolato, Rita de Cassia Marqueti, Jonato Prestes, Ramires Alsamir Tibana, Elaine Cristina Leite Pereira, Ivo Vieira de Sousa Neto, João Luiz Quagliotti Durigan, Carlos Alberto da Silva
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Physiology
Subjects:
Denervation
Leucine
muscle atrophy
rehabilitation.
synthesis pathways
degradation pathways
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00073/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00073/full

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