Primary Spinal OPC Culture System from Adult Zebrafish to Study Oligodendrocyte Differentiation In Vitro

Endogenous oligodendrocyte progenitor cells (OPCs) are a promising target to improve functional recovery after spinal cord injury (SCI) by remyelinating denuded, and therefore vulnerable, axons. Demyelination is the result of a primary insult and secondary injury, leading to conduction blocks and lo...

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Bibliographic Details
Main Authors: Volker Kroehne, Vasiliki Tsata, Lara Marrone, Claudia Froeb, Susanne Reinhardt, Anne Gompf, Andreas Dahl, Jared Sterneckert, Michell M. Reimer
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
OPC
OL
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2017.00284/full