Expression of 1N3R-Tau isoform inhibits cell proliferation by inducing S phase arrest in N2a cells.

Tau is a microtubule-associated protein implicated in neurodegenerative tauopathies. Six tau isoforms are generated from a single gene through alternative splicing of exons 2, 3 and 10 in human brain. Differential expression of tau isoforms has been detected in different brain areas, during neurodev...

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Main Authors: Li Li, Zhi-Peng Xu, Gong-Ping Liu, Cheng Xu, Zhi-Hao Wang, Xiao-Guang Li, En-Jie Liu, Juan Zeng, Da-Min Chai, Wen-Long Yao, Jian-Zhi Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4378987?pdf=render