Classical NF-κB Metabolically Reprograms Sarcoma Cells Through Regulation of Hexokinase 2

Classical NF-κB Metabolically Reprograms Sarcoma Cells Through Regulation of Hexokinase 2

BackgroundMetabolic reprogramming has emerged as a cancer hallmark, and one of the well-known cancer-associated metabolic alterations is the increase in the rate of glycolysis. Recent reports have shown that both the classical and alternative signaling pathways of nuclear factor κB (NF-κB) play impo...

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Bibliographic Details
Main Authors: Priya Londhe, Peter Y. Yu, Yuichi Ijiri, Katherine J. Ladner, Joelle M. Fenger, Cheryl London, Peter J. Houghton, Denis C. Guttridge
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Oncology
Subjects:
sarcoma
nuclear factor kappa B
metabolism
hexokinase
rhabdomyosarcoma
osteosarcoma
Online Access:http://journal.frontiersin.org/article/10.3389/fonc.2018.00104/full

Internet

http://journal.frontiersin.org/article/10.3389/fonc.2018.00104/full

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