Bioinformatics and functional analysis of an Entamoeba histolytica mannosyltransferase necessary for parasite complement resistance and hepatical infection.

The glycosylphosphatidylinositol (GPI) moiety is one of the ways by which many cell surface proteins, such as Gal/GalNAc lectin and proteophosphoglycans (PPGs) attach to the surface of Entamoeba histolytica, the agent of human amoebiasis. It is believed that these GPI-anchored molecules are involved...

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Bibliographic Details
Main Authors: Christian Weber, Samantha Blazquez, Sabrina Marion, Christophe Ausseur, Divya Vats, Mickael Krzeminski, Marie-Christine Rigothier, Rachid C Maroun, Alok Bhattacharya, Nancy Guillén
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2239303?pdf=render