Diosmetin Ameliorates Vascular Dysfunction and Remodeling by Modulation of Nrf2/HO-1 and p-JNK/p-NF-κB Expression in Hypertensive Rats

Diosmetin Ameliorates Vascular Dysfunction and Remodeling by Modulation of Nrf2/HO-1 and p-JNK/p-NF-κB Expression in Hypertensive Rats

Diosmetin is a citrus flavonoid that has antioxidant and anti-inflammatory effects. This study examined the effect of diosmetin on blood pressure and vascular alterations and its underlying mechanisms in experimentally hypertensive rats. Male Sprague rats were administered Nω-nitro-<span style=&q...

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Bibliographic Details
Main Authors: Sariya Meephat, Patoomporn Prasatthong, Prapassorn Potue, Sarawoot Bunbupha, Poungrat Pakdeechote, Putcharawipa Maneesai
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Antioxidants
Subjects:
diosmetin
vascular function
vascular remodeling
oxidative stress
inflammation
Online Access:https://www.mdpi.com/2076-3921/10/9/1487

Internet

https://www.mdpi.com/2076-3921/10/9/1487

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