Foxc2 enhances proliferation and inhibits apoptosis through activating Akt/mTORC1 signaling pathway in mouse preadipocytes

Foxc2 enhances proliferation and inhibits apoptosis through activating Akt/mTORC1 signaling pathway in mouse preadipocytes

Forkhead box C2 (Foxc2) protein is a transcription factor in regulation of development, metabolism, and immunology. However, the regulatory mechanisms of Foxc2 on proliferation and apoptosis of preadipocytes are unclear. In this study, we found that high-fat-diet-induced obesity elevated the express...

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Bibliographic Details
Main Authors: Lu Gan, Zhenjiang Liu, Wei Jin, Zhongjie Zhou, Chao Sun
Format: Article
Language:English
Published: Elsevier 2015-08-01
Series:Journal of Lipid Research
Subjects:
forkhead box C2
transcription factor
cell death
fat
cell signaling
protein kinase B/mammalian target of rapamycin C1 signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520355243

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http://www.sciencedirect.com/science/article/pii/S0022227520355243

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