Li–Fraumeni syndrome in adult patients with acute lymphoblastic leukemia

Li–Fraumeni syndrome in adult patients with acute lymphoblastic leukemia

Background. LiFraumeni syndrome (LFS) is a rare, autosomal dominant, hereditary disorder that is characterized by an increased risk for certain types of cancer, acute lymphoblastic leukemia (ALL), particularly. Germline TP53 mutations are associated with LFS. Genetic counseling and follow-up is esse...

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Bibliographic Details
Main Authors: Kseniia I. Zarubina, Elena N. Parovichnikova, Vadim L. Surin, Olesia S. Pshenichnikova, Olga A. Gavrilina, Galina A. Isinova, Vera V. Troitskaya, Andrei N. Sokolov, Irina V. Galtseva, Nikolai M. Kapranov, Juliia O. Davydova, Tatiana N. Obukhova, Elena E. Nikulina, Andrei B. Sudarikov, Valerii G. Savchenko
Format: Article
Language:Russian
Published: "Consilium Medicum" Publishing house 2021-07-01
Series:Терапевтический архив
Subjects:
acute lymphoblastic leukemia
hereditary predisposition
li–fraumeni syndrome
tp53 mutations
Online Access:https://ter-arkhiv.ru/0040-3660/article/viewFile/76306/56901

Internet

https://ter-arkhiv.ru/0040-3660/article/viewFile/76306/56901

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