Sub-regional hippocampal injury is associated with fornix degeneration in Alzheimer's disease

Sub-regional hippocampal injury is associated with fornix degeneration in Alzheimer's disease

We examined in vivo evidence of axonal degeneration in association with neuronal pathology in Alzheimer’s disease (AD) through analysis of fornix microstructural integrity and measures of hippocampal subfield atrophy. Based on known anatomical topography, we hypothesized that the local thickness of...

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Bibliographic Details
Main Authors: Dong Young Lee, Evan eFletcher, Owen Thomas Carmichael, Baljeet eSingh, Dan eMungas, Bruce eReed, Oliver eMartinez, Michael H Buonocore, Maria ePersianinova, Charles eDeCarli
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-04-01
Series:Frontiers in Aging Neuroscience
Subjects:
Hippocampus
Mild Cognitive Impairment
Alzheimer's disease
Fornix
fractional anisotropy
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2012.00001/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnagi.2012.00001/full

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