Roles of dopamine receptor on chemosensory and mechanosensory primary cilia in renal epithelial cells

Roles of dopamine receptor on chemosensory and mechanosensory primary cilia in renal epithelial cells

Dopamine plays a number of important physiological roles. However, activation of dopamine receptor type-5 (DR5) and its effect in renal epithelial cells have not been studied. Here, we show for the first time that DR5 is localized to primary cilia of LLCPK kidney cells. Renal epithelial cilia are...

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Bibliographic Details
Main Authors: Viralkumar eUpadhyay, Brian eMuntean, Jang eHwang, Sarmed eKathem, Wissam eAbou-Alaiwi, Surya eNauli
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-02-01
Series:Frontiers in Physiology
Subjects:
Pharmacology
Physiology
Mechanotransduction
Mechanosensation
fluid shear stress
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00072/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00072/full

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