Refined RIP-seq protocol for epitranscriptome analysis with low input materials.
N6-Methyladenosine (m6A) accounts for approximately 0.2% to 0.6% of all adenosine in mammalian mRNA, representing the most abundant internal mRNA modifications. m6A RNA immunoprecipitation followed by high-throughput sequencing (MeRIP-seq) is a powerful technique to map the m6A location transcriptom...
Main Authors: | , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-09-01
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Series: | PLoS Biology |
Online Access: | http://europepmc.org/articles/PMC6136692?pdf=render |