The leucine zipper domains of the transcription factors GCN4 and c-Jun have ribonuclease activity.

Basic-region leucine zipper (bZIP) proteins are one of the largest transcription factor families that regulate a wide range of cellular functions. Owing to the stability of their coiled coil structure leucine zipper (LZ) domains of bZIP factors are widely employed as dimerization motifs in protein e...

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Bibliographic Details
Main Authors: Yaroslav Nikolaev, Christine Deillon, Stefan R K Hoffmann, Laurent Bigler, Sebastian Friess, Renato Zenobi, Konstantin Pervushin, Peter Hunziker, Bernd Gutte
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2874015?pdf=render