Periodontal pathogens promote cancer aggressivity via TLR/MyD88 triggered activation of Integrin/FAK signaling that is therapeutically reversible by a probiotic bacteriocin

Periodontal pathogens promote cancer aggressivity via TLR/MyD88 triggered activation of Integrin/FAK signaling that is therapeutically reversible by a probiotic bacteriocin

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Epidemiological studies reveal significant associations between periodontitis and oral cancer. However, knowledge about the contribution of periodontal pathogens to oral cancer and potential regulatory mechanisms involved is limited. Previously, we showed that nisin, a bacteriocin and commonly used...

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Bibliographic Details
Main Authors: Pachiyappan Kamarajan, Islam Ateia, Jae M. Shin, J. Christopher Fenno, Charles Le, Ling Zhan, Ana Chang, Richard Darveau, Yvonne L. Kapila, Renée M. Tsolis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-10-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529280/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529280/?tool=EBI

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