Mito-Nuclear Communication in Hepatocellular Carcinoma Metabolic Rewiring

As the main metabolic and detoxification organ, the liver constantly adapts its activity to fulfill the energy requirements of the whole body. Despite the remarkable adaptive capacity of the liver, prolonged exposure to noxious stimuli such as alcohol, viruses and metabolic disorders results in the...

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Bibliographic Details
Main Authors: Tommaso Mello, Irene Simeone, Andrea Galli
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cells
Subjects:
HCC
NRF
HIF
Online Access:https://www.mdpi.com/2073-4409/8/5/417