Monobac System–A Single Baculovirus for the Production of rAAV

Monobac System–A Single Baculovirus for the Production of rAAV

Large-scale manufacturing of rAAV is a bottleneck for the development of genetic disease treatments. The baculovirus/Sf9 cell system underpins the first rAAV treatment approved by EMA and remains one of the most advanced platforms for rAAV manufacturing. Despite early successes, rAAV is still a comp...

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Bibliographic Details
Main Authors: Lionel Galibert, Aurélien Jacob, Adrien Savy, Yohann Dickx, Delphine Bonnin, Christophe Lecomte, Lise Rivollet, Peggy Sanatine, Marjorie Boutin Fontaine, Christine Le Bec, Otto-Wilhelm Merten
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Microorganisms
Subjects:
rAAV
baculovirus
gene therapy
Online Access:https://www.mdpi.com/2076-2607/9/9/1799

Internet

https://www.mdpi.com/2076-2607/9/9/1799

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