Paradoxical Role of Matrix Metalloproteinases in Liver Injury and Regeneration after Sterile Acute Hepatic Failure

Paradoxical Role of Matrix Metalloproteinases in Liver Injury and Regeneration after Sterile Acute Hepatic Failure

Acetaminophen (APAP) poisoning is one of the leading causes of acute hepatic failure and liver transplantation is often the only lifesaving alternative. During the course of hepatocyte necrosis, an intense accumulation of neutrophils is often observed within the liver microenvironment. Despite the c...

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Bibliographic Details
Main Authors: Débora Moreira Alvarenga, Matheus Silvério Mattos, Mateus Eustáquio Lopes, Sarah Cozzer Marchesi, Alan Moreira Araújo, Brenda Naemi Nakagaki, Mônica Morais Santos, Bruna Araújo David, Viviane Aparecida De Souza, Érika Carvalho, Rafaela Vaz Sousa Pereira, Pedro Elias Marques, Kassiana Mafra, Hortência Maciel de Castro Oliveira, Camila Dutra Moreira de Miranda, Ariane Barros Diniz, Thiago Henrique Caldeira de Oliveira, Mauro Martins Teixeira, Rafael Machado Rezende, Maísa Mota Antunes, Gustavo Batista Menezes
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Cells
Subjects:
neutrophil
matrix metalloproteinases
liver injury
sterile inflammation
Online Access:https://www.mdpi.com/2073-4409/7/12/247

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https://www.mdpi.com/2073-4409/7/12/247

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