An Optimized Method to Generate Human Active Osteoclasts From Peripheral Blood Monocytes

An Optimized Method to Generate Human Active Osteoclasts From Peripheral Blood Monocytes

Osteoclasts (OCs), the bone-resorbing cells, play a key role in skeletal development and adult bone remodeling. They also participate in the pathogenesis of various bone disorders. One of the major technical difficulties in the generation of OCs, when working on human material, is the ability to ach...

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Bibliographic Details
Main Authors: Dina Abdallah, Marie-Laure Jourdain, Julien Braux, Christine Guillaume, Sophie C. Gangloff, Jacky Jacquot, Frédéric Velard
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Immunology
Subjects:
human peripheral blood mononuclear cells
osteoclasts
vitamin D3
dentin matrix resorption
CD14+ monocytes
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00632/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00632/full

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