DAMEfinder: a method to detect differential allele-specific methylation

Abstract Background DNA methylation is a highly studied epigenetic signature that is associated with regulation of gene expression, whereby genes with high levels of promoter methylation are generally repressed. Genomic imprinting occurs when one of the parental alleles is methylated, i.e., when the...

Full description

Bibliographic Details
Main Authors: Stephany Orjuela, Dania Machlab, Mirco Menigatti, Giancarlo Marra, Mark D. Robinson
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Epigenetics & Chromatin
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13072-020-00346-8