4-Hydroxyphenylpyruvate Dioxygenase-Like Protein Promotes Pancreatic Cancer Cell Progression and Is Associated With Glutamine-Mediated Redox Balance

4-Hydroxyphenylpyruvate Dioxygenase-Like Protein Promotes Pancreatic Cancer Cell Progression and Is Associated With Glutamine-Mediated Redox Balance

Tumor cells develop a series of metabolic reprogramming mechanisms to meet the metabolic needs for tumor progression. As metabolic hubs in cells, mitochondria play a significant role in this process, including energy production, biosynthesis, and redox hemostasis. In this study, we show that 4-hydro...

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Bibliographic Details
Main Authors: Xianglai Ye, Xiujuan Wei, Jing Liao, Peipei Chen, Xueyun Li, Yulong Chen, Yue Yang, Qiongya Zhao, Hongwei Sun, Liming Pan, Guorong Chen, Xujun He, Jianxin Lyu, Hezhi Fang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Oncology
Subjects:
mitochondria
pancreatic ductal adenocarcinoma
metabolic reprogramming
glutamine
redox balance
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.617190/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2020.617190/full

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