Activation of the AMP-related kinase (AMPK) induces renal vasodilatation and downregulates Nox-derived reactive oxygen species (ROS) generation

Activation of the AMP-related kinase (AMPK) induces renal vasodilatation and downregulates Nox-derived reactive oxygen species (ROS) generation

AMP-activated protein kinase (AMPK) is a cellular energy sensor activated during energy stress to stimulate ATP production pathways and restore homeostasis. AMPK is widely expressed in the kidney and involved in mitochondrial protection and biogenesis upon acute renal ischemia, AMPK activity being b...

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Bibliographic Details
Main Authors: Claudia Rodríguez, Cristina Contreras, Javier Sáenz-Medina, Mercedes Muñoz, César Corbacho, Joaquín Carballido, Albino García-Sacristán, Medardo Hernandez, Miguel López, Luis Rivera, Dolores Prieto
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Redox Biology
Subjects:
AMPK activators
Renal arteries
IKCa channels
KATP channels
SERCA
Reactive oxygen species
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720305541

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http://www.sciencedirect.com/science/article/pii/S2213231720305541

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