Naringin Dihydrochalcone Ameliorates Cognitive Deficits and Neuropathology in APP/PS1 Transgenic Mice

Naringin Dihydrochalcone Ameliorates Cognitive Deficits and Neuropathology in APP/PS1 Transgenic Mice

Alzheimer’s disease (AD) is a multi-factorial neurodegenerative disorder with abnormal accumulation of amyloid-β (Aβ) plaques, neuroinflammation and impaired neurogenesis. Mounting evidences suggest that single-target drugs have limited effects on clinical treatment and alternative or multiple targe...

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Bibliographic Details
Main Authors: Wenjuan Yang, Keyan Zhou, Yue Zhou, Yuqian An, Tingting Hu, Jing Lu, Shichao Huang, Gang Pei
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
naringin dihydrochalcone
Alzheimer’s disease
amyloid-β
neuroinflammation
neurogenesis
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2018.00169/full

Internet

https://www.frontiersin.org/article/10.3389/fnagi.2018.00169/full

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