Biodistribution and Efficacy of Human Adipose-Derived Mesenchymal Stem Cells Following Intranodal Administration in Experimental Colitis

Biodistribution and Efficacy of Human Adipose-Derived Mesenchymal Stem Cells Following Intranodal Administration in Experimental Colitis

Mesenchymal stem cells (MSCs) have a large potential in cell therapy for treatment of inflammatory and autoimmune diseases, thanks to their immunomodulatory properties. The encouraging results in animal models have initiated the translation of MSC therapy to clinical trials. In cell therapy protocol...

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Bibliographic Details
Main Authors: Mercedes Lopez-Santalla, Pablo Mancheño-Corvo, Amelia Escolano, Ramon Menta, Olga DelaRosa, Jose Luis Abad, Dirk Büscher, Juan M. Redondo, Juan A. Bueren, Wilfried Dalemans, Eleuterio Lombardo, Marina I. Garin
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Immunology
Subjects:
adipose-derived mesenchymal stem cells
intranodal therapy
colitis
biodistribution
efficacy
immunomodulation
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00638/full

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http://journal.frontiersin.org/article/10.3389/fimmu.2017.00638/full

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