Host cytokine responses induced after overnight stimulation with novel M. tuberculosis infection phase-dependent antigens show promise as diagnostic candidates for TB disease.

Host cytokine responses induced after overnight stimulation with novel M. tuberculosis infection phase-dependent antigens show promise as diagnostic candidates for TB disease.

BACKGROUND: We previously identified Mycobacterium tuberculosis (M.tb) antigen-induced host markers that showed promise as TB diagnostic candidates in 7-day whole blood culture supernatants. The aim of the present study was to evaluate the utility of these markers further, and cross-compare results...

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Bibliographic Details
Main Authors: Paulin N Essone, Novel N Chegou, Andre G Loxton, Kim Stanley, Magdalena Kriel, Gian van der Spuy, Kees L Franken, Tom H Ottenhoff, Gerhard Walzl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4099213?pdf=render

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http://europepmc.org/articles/PMC4099213?pdf=render

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