CD4(+) cells regulate fibrosis and lymphangiogenesis in response to lymphatic fluid stasis.

Lymphedema is a chronic disorder that occurs commonly after lymph node removal for cancer treatment and is characterized by swelling, fibrosis, inflammation, and adipose deposition. Although previous histological studies have investigated inflammatory changes that occur in lymphedema, the precise ce...

Full description

Bibliographic Details
Main Authors: Jamie C Zampell, Alan Yan, Sonia Elhadad, Tomer Avraham, Evan Weitman, Babak J Mehrara
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3502174?pdf=render