Surface-modified mucoadhesive microparticles as a controlled release system for oral delivery of insulin

To overcome barriers and improve oral bioavailability of insulin delivery has been a mirage to formulation scientists due to instability of the insulin after oral administration. Microparticle (MP) composed of chitosan and snail mucin was prepared via double emulsion method for oral delivery of insu...

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Bibliographic Details
Main Authors: Momoh A. Mumuni, Frankilin C. Kenechukwu, Omeje C. Ernest, Adedokun M. Oluseun, Barikisu Abdulmumin, Darlington C. Youngson, Ofokansi C. Kenneth, Attama A. Anthony
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844019360268