Protein diffusion in mammalian cell cytoplasm.

We introduce a new method for mesoscopic modeling of protein diffusion in an entire cell. This method is based on the construction of a three-dimensional digital model cell from confocal microscopy data. The model cell is segmented into the cytoplasm, nucleus, plasma membrane, and nuclear envelope,...

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Bibliographic Details
Main Authors: Thomas Kühn, Teemu O Ihalainen, Jari Hyväluoma, Nicolas Dross, Sami F Willman, Jörg Langowski, Maija Vihinen-Ranta, Jussi Timonen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21886771/?tool=EBI