Production of amphiregulin and recovery from influenza is greater in males than females

Abstract Background Amphiregulin (AREG) is an epidermal growth factor that is a significant mediator of tissue repair at mucosal sites, including in the lungs during influenza A virus (IAV) infection. Previous research illustrates that males of reproductive ages experience less severe disease and re...

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Bibliographic Details
Main Authors: Meghan S. Vermillion, Rebecca L. Ursin, Denise I. T. Kuok, Landon G. vom Steeg, Nicholas Wohlgemuth, Olivia J. Hall, Ashley L. Fink, Eric Sasse, Andrew Nelson, Roland Ndeh, Sharon McGrath-Morrow, Wayne Mitzner, Michael C. W. Chan, Andrew Pekosz, Sabra L. Klein
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Biology of Sex Differences
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13293-018-0184-8